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Mercedes-Benz · NHTSA safety record

2021 Mercedes-Benz E 350

Every safety complaint, recall and defect investigation the US government holds on this vehicle.

13

Complaints

0

Crashes

1

Fires

0

Injuries

0

Deaths

Owners of the 2021 Mercedes-Benz E 350 have filed 13 safety complaints with NHTSA between December 2023 and August 2026. The most complained-about system is the electrical system, named in 4 of them (31%). The typical failure was reported at 38,601 miles, the median across the 2 complaints that gave an odometer reading.

NHTSA has issued 12 recalls covering this vehicle.

Recalls (12)

FUEL SYSTEM, GASOLINE:DELIVERY:FUEL PUMP

23V445000 · June 26, 2023

The defect
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2023 C-Class, E-Class, S-Class, CLS, SL, GT, GLC, GLE, GLS, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle details. The fuel pump may shutdown, which can result in a loss of drive power.
The risk
A loss of drive power can increase the risk of a crash.
The remedy
Dealers will replace the fuel pump, free of charge. Owner notification letters were mailed on June 14, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2023070012.

Mercedes-Benz USA, LLC · up to 143,551 vehicles across all model years covered

ELECTRICAL SYSTEM:SOFTWARE

22V365000 · May 20, 2022

The defect
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2017-2022 CLA-Class, GLA-Class, GLE-Class, GLS-Class, SLC-Class, A-Class, AMG GT-Class, C-Class, E-Class, S-Class, SL-Class, GLC-Class, CLS-Class, GLB-Class, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle model details. An error in the communication module's SIM card software can cause a mobile network connection failure, disabling the emergency call (eCall) system.
The risk
A disabled eCall system would prevent a vehicle occupant from contacting the emergency services call center in an emergency, potentially delaying emergency responders and increasing the risk of injury.
The remedy
The communication module software will be updated through an Over-the-Air (OTA) update or by a dealer, free of charge. Owner notification letters were mailed July 8, 2022. Owner notification letters will be mailed in phases, on July 8, 2022, May 17, 2024, July 29, 2024, and September 27, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's numbers are for this recall is 2022060005 and 2023110006.

Mercedes-Benz USA, LLC · up to 242,722 vehicles across all model years covered · fixed by software update

BACK OVER PREVENTION:DISPLAY FUNCTION

22V232000 · April 8, 2022

The defect
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2018-2021 CLA-Class, GLE/GLS-Class, A-Class, C-Class, E-Class, E-Class Coupe/Convertible, GLA/GLB-Class, GLC-Class, and CLS-Class vehicles. Please refer to MBUSA's recall report for specific vehicle model details. The rearview camera may not display the rearview image due to a software error. As such, these vehicles fail to comply with the requirements of Federal Motor Vehicle Safety Standard number 111, "Rear Visibility."
The risk
An inoperable rearview camera display reduces the driver's rear view, increasing the risk of a crash.
The remedy
Dealers will update the rearview camera software, free of charge. Owner notification letters were mailed July 15, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022060007.

Mercedes-Benz USA, LLC · up to 126,443 vehicles across all model years covered

STEERING: STEERING WHEEL/HANDLE BAR

22V189000 · March 25, 2022

The defect
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2022 C-Class, E-Class, S-Class, SL, EClass Coupe/Convertible, CLS, AMG GT 4-doors Coupe, and EQS vehicles with a heated leather steering wheel. Due to a software error in the hand detection control unit, the hands-off detection might not detect when the driver's hands are away from the steering wheel when using the Active Distance Assist DISTRONIC system.
The risk
Deactivated hands-off detection will prevent DISTRONIC system features from functioning, including warnings to grab the steering wheel and calling first responders as part of the Active Emergency Stop Assist, which can increase the risk of a crash or injury.
The remedy
Dealers will update the hand detection control unit software for the DISTRONIC system, free of charge. Owner notification letters were mailed May 6, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022040010.

Mercedes-Benz USA, LLC · up to 8,396 vehicles across all model years covered

AIR BAGS:SENSOR:SIDE IMPACT

21V527000 · July 12, 2021

The defect
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 CLS450, AMG E53, AMG CLS53, E350, E450, AMG GT43, AMG GT53, 2020 S450, S560, G550, AMG GLC63, 2020-2021 GLC300, and AMG G63 vehicles. The side crash sensor connectors may come loose, which could delay the activation of air bags and seatbelts during a side impact crash.
The risk
Air bags and seatbelts that don't function as intended can increase the risk of injury during a crash.
The remedy
Dealers will inspect and replace as necessary, the side impact crash sensors, free of charge. Owner notification letters were mailed on September 3, 2021. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2021070032/33.

Mercedes-Benz USA, LLC · up to 542 vehicles across all model years covered

SEAT BELTS:REAR/OTHER:RETRACTOR

21V483000 · June 25, 2021

The defect
Mercedes-Benz, LLC (MBUSA) is recalling certain 2021 G550, AMG G63, E350, E450, AMG CLS53, AMG E53, AMG GT43, AMG GT53, AMG GT63, 2021-2022 CLS450, and AMG E63 vehicles. The rear seat belt automatic locking retractors may deactivate early, which can prevent the child restraint system from securing properly. As such, these vehicles fail to comply with the requirements of Federal Motor Vehicle Safety Standard number 208, "Occupant Crash Protection."
The risk
An unsecured child restraint system can increase the risk of injury during a crash.
The remedy
Dealers will inspect, and replace as necessary, the rear seat belt assemblies, free of charge. Owners notified of the voluntary recall campaign by an interim letter on August 13, 2021. A final letter was mailed on September 24, 2021. Owners may contact MBUSA customer service at 1-800-367-6372.

Mercedes-Benz USA, LLC · up to 4,917 vehicles across all model years covered

BACK OVER PREVENTION: SENSING SYSTEM: CAMERA

21V354000 · May 14, 2021

The defect
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2019-2021 CLA-Class, GLE/GLS-Class, A-Class, E-Class, E-Class Coupe and Convertible, GLA/GLB-Class, GLC-Class, CLS-Class, and AMG GT-Class 4-door Coupe vehicles. Please refer to MBUSA's recall report for specific vehicle model details. The MBUX multimedia system software may cause the display to remain black, or reboot after startup. This could result in the rearview camera image not displaying properly. As such, these vehicles fail to comply with the requirements of Federal Motor Vehicle Safety Standard (FMVSS) number 111, "Rear Visibility."
The risk
A backup camera that displays a blank image reduces the driver's rear view, increasing the risk of a crash or injury.
The remedy
The multimedia system software will be updated by a dealer, or through an over-the-air (OTA) update, free of charge. Owner notification letters were mailed beginning June 28, 2021. Owners may contact MBUSA customer service at 1-800-367-6373. MBUSA's number for this recall is 2021050012.

Mercedes-Benz USA, LLC · up to 343,191 vehicles across all model years covered · fixed by software update

SEATS

21V230000 · April 1, 2021

The defect
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 C-Class, E-Class, E-Class Coupe and Convertible, GLC, CLS, AMG GT 4-door Coupe and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle model details. A faulty electrical contact within the seat position switch may prevent the driver and passenger air bags and seat belt force limiters from properly activating during a crash.
The risk
Air bags and seat belts that do not perform properly in a crash can increase the risk of injury.
The remedy
MBUSA will notify owners, and dealers will replace the seat position switches, free of charge. Owner letters were mailed May 21, 2021. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2021040016.

Mercedes-Benz USA, LLC · up to 8,634 vehicles across all model years covered

BACK OVER PREVENTION: SENSING SYSTEM: CAMERA

21V228000 · April 1, 2021

The defect
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 E350, E450, E450 Wagon, and AMG E63 vehicles. The parking control unit may fail to display the rearview camera image and cause the parking sensors to misidentify or fail to detect objects.
The risk
An inoperative rearview camera display and/or parking sensors can reduce the driver's view and awareness of what is behind the vehicle, increasing the risk of a crash.
The remedy
All affected vehicles are still within MBUSA's control. MBUSA will replace the parking control unit, free of charge. The recall began April 8, 2021. Owner may contact MBUSA customer service at 1-800-367-6372.

Mercedes-Benz USA, LLC · up to 6 vehicles across all model years covered

SEATS

21V216000 · March 26, 2021

The defect
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 E350, E450, E450 Wagon, E63S AMG, 2020 E63S AMG Wagon, and 2020-2021 E53 AMG vehicles. The passenger seat limiter may allow the seat to be positioned too close to the air bag.
The risk
A seat too close to the air bag increases the risk of injury in the event of a crash necessitating the deployment of the frontal passenger air bag.
The remedy
MBUSA will notify owners, and dealers will recalibrate the passenger seat limiter, free of charge. The recall began April 29, 2021. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2021040002.

Mercedes-Benz USA, LLC · up to 109 vehicles across all model years covered

ELECTRICAL SYSTEM:SOFTWARE

21V058000 · February 5, 2021

The defect
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2016 - 2021 CLA-Class, GLA-Class, GLE-Class, GLS-Class, SLC-Class, A-Class, GT-Class, C-Class, E-Class, S-Class, CLS-Class, SL-Class, B-Class, GLB-Class, GLC-Class, and G-Class vehicles. Please refer to the Part 573 report for specific vehicle model details. The software design of the communication module may fail to communicate the correct vehicle location for the emergency call system (eCall) in the event of a crash.
The risk
Failure of the eCall system may result in emergency responders being dispatched to the wrong location, increasing the risk of injury following a crash.
The remedy
MBUSA will notify owners, and the communication module software will be updated by a dealer, or through an over-the-air (OTA) update, free of charge. The recall began March 12, 2021. Owners may contact MBUSA customer service at 1-877-762-8267. MBUSA's number for this recall is 2021020025.

Mercedes-Benz USA, LLC · up to 1,292,258 vehicles across all model years covered · fixed by software update

SEATS

20V673000 · October 30, 2020

The defect
Mercedes-Benz USA, LLC. (MBUSA) is recalling certain 2021 E350 and E450, 2019-2021 AMG E53 and 2020-2021 AMG E63 vehicles. The front passenger seat may be missing the mechanical seat adjustment range limit stop, allowing the seat to move outside of the acceptable range in relation to the air bag.
The risk
If the front passenger seat is adjusted beyond the acceptable range in relation to the air bag, there could be an increased risk of injury in the event of a crash with air bag deployment.
The remedy
MBUSA will notify owners, and dealers will inspect for the mechanical seat adjustment range limitation for the front passenger seat and install it if necessary, free of charge. The recall began December 18, 2020. Owners may contact MBUSA customer service at 1-800-368-6372. MBUSA's number for this recall is 2020110013.

Mercedes-Benz USA, LLC. · up to 1,337 vehicles across all model years covered

What owners report

Complaints naming each system. One complaint can name several, so these add up to more than 13.

ELECTRICAL SYSTEM 4 31%
ENGINE 4 31%
BACK OVER PREVENTION 3 23%
POWER TRAIN 3 23%
FUEL/PROPULSION SYSTEM 2 15%
FUEL SYSTEM, GASOLINE 1 8%
SERVICE BRAKES 1 8%

When the complaints arrived

By the year NHTSA received them, which is not the year the failures happened. They peaked in 2024 at 5.

2023 2024 2026
2023 to 2026, the last of them a part year

In owners' own words

Quoted from NHTSA's complaint file. These are unverified accounts by the people who filed them, not findings of fault.

ELECTRICAL SYSTEM

fire

FIRE FIRE FIRE Information light came on just saying 12 Volt Battery. I sat in the car letting it idle for about 3 minutes. It began to smoke and then burst into flames. I called 911 got the fire department here but by the time they were here there was not much left. The car essentially burned to the ground and insurance has declared it a total loss. Car was in my driveway, was certainly a danger to me, to my house and to my neighbor's cars and house.

NHTSA complaint 11629406. Filed by an owner and not verified by NHTSA or by us.

SERVICE BRAKES

towed · 24,001 miles

The contact owns a 2021 Mercedes-Benz E350. The contact stated that while parking the vehicle the emergency brake independently seized. The contact stated that the vehicle abruptly stopped. The vehicle would not drive forward or backward. The contact contacted the dealer and a service technician was dispatched to the location. The service technician connected the vehicle to the diagnostic equipment. The contact was advised that the vehicle was not safe to drive. The vehicle was towed to the dealer where it was diagnosed with a failed brake caliber voltage malfunction and the brake caliber voltage needed to be replaced. The vehicle was repaired. The manufacturer was made aware of the

NHTSA complaint 11578960, quoted in part. Filed by an owner and not verified by NHTSA or by us.

POWER TRAIN
Engine misfires, lower engine power, and a lit check engine/Malfunction Indicator Lamp. Mercedes-Benz issued an Emission Service Campaign (No. 2021070006, internal code 21P1590208) to replace out-of-spec ignition coils on 657 vehicles from model year 2021, including the E-Class. My VIN was not included in the recall campaign but my vehicle is experiencing these exact symptoms as referenced in the first sentence. My vehicle has 48,000 miles.

NHTSA complaint 11755689. Filed by an owner and not verified by NHTSA or by us.

ELECTRICAL SYSTEM
Vehicle: 2021 Mercedes-Benz E350 Sedan (W213) VIN: [XXX] While operating the vehicle, the diagnostic system displayed the fault code P240200 related to the Evaporative Emission Control System (EVAP). The warning message indicated a “positive short circuit” in the fuel vapor leak diagnosis pump control circuit. The malfunction appears to involve the EVAP diagnostic module and/or associated electrical wiring near the fuel system. The affected component may be available for inspection upon request. The issue raises safety concerns because the fault involves an electrical short circuit associated with the fuel vapor control system. Potential risks may include electrical overheating, malfunction

NHTSA complaint 11736678, quoted in part. Filed by an owner and not verified by NHTSA or by us.

POWER TRAIN
With the car only have about 15,000 miles the transmission has failed . I have seen there have been recalls of other models with similar complaints of transmission failure .

NHTSA complaint 11708688. Filed by an owner and not verified by NHTSA or by us.

ENGINE
Engine keeps having a misfire that Mercedes put a TSB out for and once the misfire happen I cause the vehicle to go in a limp mode which causes the vehicle to loose power happened to me in the freeway. The car had 54K miles and Mercedes refused to repair the issue as the engine part failure isn’t common.

NHTSA complaint 11707258. Filed by an owner and not verified by NHTSA or by us.

ENGINE
My 2021 Mercedes-Benz E350 (VIN [XXX] ) developed a serious engine issue involving cylinder misfire and check engine light. The dealer diagnosed it as a leaking exhaust valve on cylinder 4, related to TSB LI01.30-P-072328, which documents valve seat wear in M260 engines. This is a known defect acknowledged by Mercedes in technical bulletins, and other customers in the U.S. have received warranty extensions or goodwill coverage. I was denied coverage even though this is a manufacturer defect that can lead to misfire, power loss, and potential stalling, posing a safety risk on the road. Mercedes-Benz USA refuses to cover the repair (~$7,600+), even though it relates to a factory-documented

NHTSA complaint 11673376, quoted in part. Filed by an owner and not verified by NHTSA or by us.

POWER TRAIN
The Mercedes E350, with 22,000 miles suffered a catastrophic transmission failure while driving on the highway. I managed to exit the highway but the car could not be moved and left me stranded.

NHTSA complaint 11672435. Filed by an owner and not verified by NHTSA or by us.

Compare

Other years of the Mercedes-Benz E 350

Model year Complaints Recalls Deaths
2022 8 3
2020 8 6
2016 51 5
2015 31 6
2014 277 8
2013 161 6
2012 215 7
2011 223 5
2010 183 4

Other 2021 Mercedes-Benz models

Every Mercedes-Benz on this site — 216 vehicles, 576 recall campaigns and 1 open investigation .

If this is your car and a dealer keeps failing to fix it, your state's lemon law may require the manufacturer to replace it or buy it back. What each state asks for , read from the statutes.

Where these numbers come from

A complaint is one owner's account and has not been verified by NHTSA or by us. A vehicle with more complaints is not necessarily worse: models that sold in larger numbers collect more of them. How this is counted.

Compiled and maintained by
Independent developer and analyst